Diflucan (fluconazole), like all medications, has side effects when used. Common side effects of Diflucan include nausea, vomiting, diarrhea, dizziness, and abdominal pain. Other side effects include exfoliative skin disorders and cardiac arrhythmias (especially QT prolongation). Diflucan should not be used by people with liver or kidney dysfunction. Diflucan capsules contain lactose and should not be given to people with rare hereditary problems of galactose intolerance, Lapp lactase deficiency, or glucose-galactose malabsorption. Diflucan is a potent inhibitor of cytochrome P450 isoenzymes and caution should be exercised when Diflucan is used with other medications. It is not recommended to drink alcohol while taking Diflucan. All questions regarding Diflucan’s side effects should be directed to one’s medical provider and pharmacist.