Hydrochlorothiazide is a prescription medication that can cause side effects in some people. Side effects related to hydrochlorothiazide use include nausea, diarrhea, weakness, electrolyte imbalances, myopia and acute angle-closure glaucoma. People with allergy or bronchial asthma should only use hydrochlorothiazide if directed to do so by their medical provider. People who do not produce urine or have severe kidney disease should not use hydrochlorothiazide. Additionally, anyone with a hypersensitivity or allergy to hydrochlorothiazide should avoid using it. Before using hydrochlorothiazide, it is important to discuss and any all questions about potential side effects with one’s medical provider and pharmacist.