Januvia

More information

• Usage

  Januvia contains contains a compound known as sitagliptin phosphate. Januvia, similar to Tradjenta, belongs to a class of medications known as dipeptidyl peptidase-4 (DPP-4) inhibitors. In other words, Januvia blocks the activity of the dipeptidyl peptidase-4 (DPP-4) enzyme. Sitagliptin is thought to slow the inactivation of incretin hormones which are involved in the regulation of glucose homeostasis. By increasing incretin levels, Januvia is thought to help decrease glucagon levels and increase insulin release. Most of the sitagliptin in Januvia is excreted in the urine. Sitagliptin (Januvia) is also utilized in combination with metformin in a medication called Janumet.

• Januvia – Side Effects

  Side effects of Januvia include, but are not limited to, headache, nasopharyngitis, and upper respiratory tract infection. There have been reports of Januvia causing renal failure, pancreatitis, and hypoglycemia, especially when Januvia is used with other medications. Januvia can cause an allergic reaction and anyone with a known hypersensitivity or allergy to Januvia or sitagliptin should not use the medication. Januvia and alcohol should not be used together. Before using Januvia, it is important to discuss questions and concerns about Januvia’s side effects with one’s pharmacist and medical provider.

• Cost Information

  Januvia is expensive if one is paying without insurance. At many pharmacies, Januvia will cost up to $20 per tablet. There are some ways that can potentially bring Januvia’s cost down. One way is to look for Januvia coupons online through the manufacturer or other third-party resources. Another way to bring Januvia’s cost down is to try and use insurance to pay for the medication. Farmington Drugs & Medical Supplies takes pride in offering the most cost efficient services and prescriptions to our patients.

• Dosage

  The starting dose for Januvia is often 100mg one daily. The dosage of Januvia should be adjusted in people with kidney disease. Januvia tablets should be swallowed whole and not crushed when ingested. Januvia may interact with other drugs such as digoxin when taken concomitantly. After oral administration of sitagliptin 100 mg, peak plasma concentrations are reached within 4 hours with an apparent terminal half-life of 12.4 hours. Januvia is available as Januvia 100 mg tablets, Januvia 50 mg tablets and Januvia 25 mg tablets. Januvia 100 mg tablets are beige, round, film-coated tablets. The 50 mg tablets are light beige, round, film-coated tablets while the Januvia 25 mg tablets are pink, round, film-coated tablets. Sitagliptin phosphate monohydrate itself is a powder that is white to off-white in color and soluble in water.

• FDA Information

  Click here for FDA information

Given the evolving nature of medicine and science, this information might not be accurate and should not be construed as medical advice or diagnosis / treatment recommendations. Please consult a licensed medical provider if you have additional questions.