Prior to using naproxen sodium, it is important to discuss side effects with one’s medical provider and pharmacist. Like other NSAID medications, naproxen can cause side effects. Side effects that can result from Naprosyn use include headache, dizziness, heartburn, nausea, constipation, and drowsiness. More serious side effects include liver and kidney toxicity, changes in blood pressure and heart failure. Naprosyn can increase one’s risk of serious thrombotic events such as stroke and myocardial infarction as well as serious gastrointestinal events such as ulceration, bleeding and perforation of the stomach and intestines. People who have a known hypersensitivity to generic naprosyn or any of its branded versions should not use the medication. Naproxen and alcohol should not be used together. People who have had a coronary artery bypass graft surgery should not use Naprosyn.